Latent syphilis: immunoglobulins reactive in immunofluorescence and other serological tests.

نویسندگان

  • A J Julian
  • L C Logan
  • L C Norins
  • A T Scotti
چکیده

Study of sera from 69 patients with untreated or inadequately treated latent syphilis revealed that immunoglobulin (Ig)G antibodies made up the bulk of the fluorescent treponemal antibody-absorption (FTA-ABS)-test reactivity found in the sera. IgM and IgA antibodies also contributed in some cases. Venereal Disease Research Laboratory slide-test reactivity was found in both 19 and 7S serum fractions, whereas Treponema pallidum immobilization-test reactivity was found mainly in the 7S fraction.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Fluorescent treponemal antibody-absorption (FTA-ABS) test in patients with aortic valvular insufficiency.

Aortic valvular insufficiency caused by syphilis cannot be differentiated by murmur or other clinical characteristics from other causes of aortic insufficiency, and the aid of serological tests is often sought. Routine serological tests for syphilis, such as the VDRL slide test, which utilize cardiolipin antigens, are reactive in only 75 to 95 per cent. of patients with cardiovascular syphilis ...

متن کامل

Studies of syphilitic antibodies. II. Substances responsible for biological false positive sero-reactions.

It has been generally assumed that the substances responsible for biological false positive (BFP) seroreactions for syphilis are antibodies of the same kind as the syphilitic anti-lipoidal antibodies. However, the available evidence for this view is meagre and mainly circumstantial. It has been observed that in the VDRL test substitution of the cardiolipin in the antigen by certain surface-acti...

متن کامل

Are serological tests of value in diagnosing and monitoring response to treatment of syphilis in patients infected with human immunodeficiency virus?

To assess the value of serological tests in diagnosing and monitoring the response to treatment of syphilis in patients infected with the human immunodeficiency virus (HIV), case notes of eight homosexual men with a history of treated syphilis, positive reactions to serological tests for syphilis, and documented subsequent conversion to HIV seropositivity were studied. No change was noted in se...

متن کامل

Diagnosis of neurosyphilis by examination of the cerebrospinal fluid.

Thirty-six patients with reactive results in the cerebrospinal fluid to the Treponema pallidum haemagglutination assay (CSF-TPHA) were investigated by further serological tests for confirmation of active neurosyphilis. The results of the TPHA and fluorescent treponemal antibody tests were reactive in all CSF samples from patients with acute untreated neurosyphilis and from most patients with la...

متن کامل

Early syphilis: serological treatment response to doxycycline/tetracycline versus benzathine penicillin.

INTRODUCTION Benzathine penicillin G is the treatment of choice for syphilis, but doxycycline and tetracycline are effective second-line treatments. The objective of this study was to assess the serological response to treatment for early syphilis with benzathine penicillin compared with doxycycline or tetracycline. METHODOLOGY We examined rapid plasma regain (RPR) serological test results of...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:
  • Infection and immunity

دوره 3 4  شماره 

صفحات  -

تاریخ انتشار 1971